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corresponding to the α-Gal epitope (Galα1-3Galβ1-4GlcNAc) that is the target of naturally occurring human anti-Gal antibodies and is central to xenotransplantation and anti-Gal immunology research
Abnormal Akt signaling in bladder epithelial cell explants from patients with interstitial cystitis/bladder pain syndrome can be induced by antiproliferative factor treatment of normal bladder cells
The sugar hydroxyl groups are protected as three acetate esters (Ac3)
or enzymatic studies rather than a chain-extendable SPPS building block
Oleovitamin D2-d6
ES031000: 4-Methylumbelliferyl α-N-glycolylneuraminic acid Pack Size:2 mg corresponding to the α-Gal epitopeC21H25NO12 483. 42 A 4 methylumbelliferyl (MU) glycoside of N glycolylneuraminic acid (Neu5Gc), a sialic acid variant carrying an extra hydroxyl on the N acyl group and found in most mammals but not normally in humans. Used as a fluorogenic substrate for sialidases (neuraminidases) with selectivity or preference for Neu5Gc containing sialosides; sialidase catalyzed cleavage of the glycosidic bond releases free Neu5Gc and 4 methylumbelliferone. 4
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